Autologous Stem Cell Treatment (Regenera Activa) for Hair Loss Treatment in Türkiye
Hair loss often develops gradually, influenced by genetics, hormones, and changes within the scalp’s microenvironment. Modern regenerative medicine offers solutions that work directly with the body’s own biological systems, and one of the most reliable among them is Autologous Stem Cell Treatment using the Regenera Activa system.
This minimally invasive, FDA-approved micrograft technology uses viable cells taken from the patient’s own tissue to stimulate dormant follicles, slow miniaturization, and improve overall hair density. At Dr. Serkan Aygın Clinic in Istanbul, Regenera Activa is integrated into personalized treatment plans for patients experiencing early-to-moderate hair thinning, or those seeking to enhance the results of hair transplantation.
Doku Clinic is a brand of Dr. Serkan Aygın.
A Biological Approach to Hair Loss and Scalp Health
Autologous Stem Cell Therapy works by harvesting tissue from a small, discreet area of the scalp and processing it into micrografts rich in progenitor cells, growth factors, and extracellular matrix components. Unlike PRP — which uses blood components — Regenera Activa utilizes living, active cells that directly participate in tissue regeneration.
Because the treatment uses the patient’s own biological material, it is biocompatible, safe, and highly effective for supporting natural hair regrowth without surgery or medication.
What Is Regenera Activa?
Regenera Activa is an FDA-approved, single-session autologous stem cell therapy designed to support the treatment of androgenetic alopecia and progressive hair thinning. The system uses a patented micrografting technique that isolates regenerative cells from a tiny biopsy sample.
These micrografts contain:
- Progenitor cells (early-stage regenerative cells)
- Dermal papilla–associated cells
- Growth factors that regulate follicle activity
- Extracellular matrix fragments that support tissue structure
- Signaling molecules that promote repair and regeneration
The result is an injectable solution capable of stimulating follicular regeneration and improving the scalp’s biological environment.
Why This Matters for Hair
Hair follicles rely on healthy dermal papilla cells to grow. In thinning hair, these cells weaken, shrink, and eventually stop functioning. Regenera Activa reintroduces new regenerative input into the scalp, helping dormant follicles “wake up” and miniaturized follicles regain function.
How Autologous Stem Cell Therapy Works (Regenera Activa Process)
Autologous Stem Cell Therapy with Regenera Activa operates through three carefully controlled steps:
1. Micrograft Extraction
A 3 mm punch biopsy is taken from behind the ear — an area typically rich in healthy follicular tissue and shielded from sun exposure.
- Procedure is quick (minutes)
- Local anesthesia is used
- Small wound heals in 3–4 days with no visible scarring
This biopsy contains countless regenerative cells essential for hair formation.
2. Micrograft Processing (Regenera System)
The tissue sample is placed inside the Regenera Activa device, which uses mechanical filtration and fragmentation to create a suspension that contains:
- Viable progenitor cells
- Stem cell–associated factors
- Extracellular matrix components
- Natural growth factors
Unlike PRP — where cells are not viable and degrade within weeks — these micrografts offer long-term regenerative activity, often lasting up to a year.
3. Injection Into the Scalp
The prepared micrograft solution is injected into areas affected by thinning.
- Similar to mesotherapy
- Targets the dermal layer where follicles reside
- Procedure takes about 20–30 minutes
Once injected, the micrografts interact with existing follicles, supporting cellular repair and stimulating growth.
Biological Effects on Hair Follicles
Stimulating Dormant Follicles
Regenera Activa helps re-activate follicles that have entered a resting or weakened state.
Reversing Miniaturization
Miniaturized follicles regain structure, improving hair thickness and strength.
Supporting Dermal Papilla Regeneration
The treatment enhances the activity of dermal papilla cells, the core of hair formation.
Improving Vascular Supply
Micrografts support microcirculation, ensuring follicles receive better oxygen and nutrients.
Prolonging the Growth (Anagen) Phase
Hair stays in the active growing phase longer, leading to improved density.
Stabilizing Hair Shedding
Many patients experience noticeable reduction in shedding within weeks.
Regenera Activa vs Other Regenerative Hair Treatments
| Feature | Regenera Activa | PRP / Magellan PRP | Alloblast / Exosome |
|---|---|---|---|
| Source | Patient’s own tissue (micrografts) | Patient’s blood | Donor cell-derived |
| Contains stem/progenitor cells? | Yes — viable | No | No (cell-free) |
| Main Mechanism | Tissue regeneration | Growth factor release | Regenerative signaling |
| Number of Sessions | Typically 1 | 3–4 sessions | 3–4 sessions |
| Duration of Effect | Up to 1 year | Weeks to months | Months |
| Ideal For | Early thinning, transplant support | Mild shedding, scalp support | Scalp rejuvenation, inflammation reduction |
This comparison helps patients understand where each treatment fits in their hair restoration plan.
Benefits for Hair and Scalp Health
Reduces Hair Loss
Stabilizes shedding by strengthening weak follicles.
Thickens Existing Hair
Miniaturized hairs gain volume and structural integrity.
Improves Density Over Time
New hairs emerge while existing ones become stronger.
Long-Lasting Regenerative Effect
One treatment delivers visible results for up to 12 months.
Enhances Scalp Quality
Supports collagen and elastin production in the skin.
Safe and Biocompatible
Uses the patient’s own cells, with minimal risk of reaction.
Pre- and Post-Hair Transplant Applications
Before Hair Transplantation
Before hair transplantation, Autologous Stem Cell Therapy with Regenera Activa helps prepare the scalp and donor area for the surgical process. By delivering regenerative cells directly into the tissue, the treatment strengthens existing follicles, improves scalp quality, and reduces underlying inflammation. This biological preparation creates a healthier, more resilient environment for graft placement, supporting both smoother surgery and improved long-term transplant outcomes. 
After Hair Transplantation:
Following a hair transplant, Regenera Activa Autologous Stem Cell Therapy provides additional support during the healing phase. It helps grafts adapt more quickly, reduces post-surgery shedding, and encourages earlier growth. Many patients notice thicker, stronger transplanted hairs and a more natural-looking density over time.
Who Is Regenera Activa Recommended For?
Ideal for:
- Early-to-moderate androgenetic alopecia
- Men and women with diffuse thinning
- Patients preparing for a hair transplant
- Patients recovering from a hair transplant
- Individuals seeking one-time regenerative therapy
- Those sensitive to medication or unable to use minoxidil or finasteride
Not recommended for:
- Pregnant or breastfeeding individuals
- Patients with active cancer
Treatment Plan & Expectations
- Session time: ~30 minutes
- Pain level: Mild (local anesthesia used)
- Healing: Biopsy area heals in 3–4 days
- Number of sessions: Typically one, repeat yearly if needed
- Results:
- 1 month → reduced shedding
- 3 months → improved texture and volume
- 6 months → visible density
- 12 months → full effect
Regenera Activa at Dr. Serkan Aygın Clinic
Founded by Specialist Dermatologist Dr. Serkan Aygın and Melda Aygın, Doku Clinic and Dr. Serkan Aygın Clinic operate within the same medical ecosystem, uniting expertise in hair restoration, medical aesthetics, and regenerative medicine.
This integrated structure ensures that every Autologous Stem Cell Therapy (Regenera Activa) protocol is performed with clinical precision, advanced technology, and a deeply patient-centered approach.
A Regenerative Hair Loss Treatment Trusted in Türkiye
Autologous Stem Cell Therapy with Regenera Activa offers a biologically driven, minimally invasive option for stabilizing thinning hair and improving long-term follicle health.
At Dr. Serkan Aygın Clinic in Istanbul, this treatment is integrated into personalized hair restoration plans, supporting both natural hair growth and the success of hair transplantation.
For individuals seeking advanced, medically supervised hair loss treatments in Türkiye, Regenera Activa provides a reliable and scientifically grounded path toward stronger, healthier hair.Doku Clinic is a brand of Dr. Serkan Aygın.
Frequently Asked Questions
What exactly is Autologous Stem Cell Therapy (Regenera Activa)?
Is Regenera Activa painful?
Most patients report mild discomfort during the 3 mm biopsy and injection phase. Local anesthesia is applied, and the procedure is generally well tolerated.
How long does the Regenera Activa procedure take?
Usually 30 minutes from start to finish.
You can return to normal activities the same day.
How much does Regenera Activa cost in Türkiye?
Costs vary based on clinic expertise, medical team, and session type.
In Türkiye, the average range is €900–€2,000, depending on the patient’s needs and whether treatment is combined with PRP or hair transplantation.
Prices are often more affordable compared to Europe due to Türkiye’s medical tourism structure.
When will I start seeing results?
- 4–6 weeks: less shedding
- 3 months: increased thickness and improved hair texture
- 6–9 months: visible density
- 12 months: full regenerative effect
Hair continues to improve as follicles stabilize.
How long do the results last?
Most patients enjoy results for 9–18 months, depending on the stage of hair loss and scalp biology.
Some choose a maintenance session once a year.
Is Regenera Activa a one-time treatment?
Yes, in most cases, one session is enough to see meaningful improvement.
Patients with progressive genetic hair loss may repeat the procedure yearly.
Can Regenera Activa stop hair loss completely?
It can significantly slow down and stabilize shedding, especially in early-to-moderate stages.
Advanced baldness may require hair transplantation instead.
Is Regenera Activa safe?
Yes. The procedure uses your own cells, making it biocompatible, low-risk, and well tolerated.
Are there side effects?
Most are mild and temporary:
- Slight redness
- Mild soreness
Small biopsy area sensitivity. All resolve within a few days.
Is Regenera Activa better than PRP?
For many patients, yes.
Key differences:
- Regenera Activa uses viable stem/progenitor cells, not just platelets
- Results last longer (up to a year)
- Usually requires only one session
- Stronger effect on miniaturized follicles
- Better synergy with hair transplantation
PRP is still valuable for scalp health, but Regenera Activa has
deeper regenerative potential.
Can Regenera Activa thicken existing hair?
Yes. It is especially effective for thin, weak, miniaturized hair, helping it grow thicker and stronger over time.
Does Regenera Activa grow new hair?
It can help reactivate dormant follicles, leading to visible new growth in many patients with early-stage hair thinning.
Is Regenera Activa suitable for women?
Absolutely. Women with diffuse thinning, postpartum shedding, or early androgenetic alopecia respond very well to this treatment.
Can Regenera Activa help after hair transplantation?
Yes, this is one of its strongest indications.
It helps:
- Improve graft survival
- Speed up healing
- Reduce shock loss
- Strengthen transplanted follicles
- Enhance long-term density
Many patients choose Regenera Activa before and after transplantation.
How does Regenera Activa support hair transplant results?
Your dermatologist (from your transcript) explains it perfectly:
- It helps follicles grow 3–4 hairs per follicle instead of one
- It speeds up early growth in the first 3 months
- It improves thickness and hair caliber
This makes transplant results look denser, fuller, and more natural.
Can Regenera Activa replace hair transplantation?
Not in advanced baldness.
But in early-to-moderate thinning, it can delay or reduce the need for surgery.
Who should not get Regenera Activa?
- Pregnant and breastfeeding individuals
- Patients with active cancer
- People with bleeding disorders
- Individuals with scalp infections
Is Regenera Activa available in İstanbul, Türkiye?
Yes. It is performed at Dr. Serkan Aygın Clinic in Istanbul,
one of the leading centers for hair restoration and regenerative hair treatments in Türkiye.
