Regenerate, Revitalize, and Restore Hair Naturally
The science of hair restoration has evolved far beyond surgery. Today, regenerative medicine offers new, evidence-based methods to repair and reactivate the scalp’s natural healing systems.
One of the most advanced of these innovations is Alloblast (Fibroblast) Stem Cell Therapy — a cell-free regenerative treatment that uses fibroblast-derived bioactive proteins to restore scalp vitality and stimulate dormant hair follicles.
At Dr. Serkan Aygın Clinic, Alloblast Therapy is used as part of a comprehensive, medically guided approach to hair restoration — both before and after transplantation — to enhance follicle survival, improve healing, and support stronger, thicker hair growth.
This page provides a detailed overview of what Alloblast Therapy is, how it works, and why it has become a preferred choice in the next generation of non-surgical regenerative hair treatments.
What Is Alloblast Therapy?
Alloblast Therapy belongs to a new class of regenerative hair loss treatments known as cell-free stem cell therapies.
Instead of using live cells from the patient’s own tissue, this approach delivers fibroblast-derived growth factors and cytokines — the key signaling molecules responsible for cellular repair and tissue regeneration.
Fibroblasts are specialized cells found in the skin’s connective tissue. They play a vital role in producing collagen, elastin, and extracellular matrix components, maintaining both the structure and function of the scalp.
Doku Clinic is a brand of Dr. Serkan Aygın.
The Science Behind It
During the Alloblast process, donor fibroblast cells are cultivated under strict laboratory conditions. Scientists extract the regenerative secretome — a combination of bioactive peptides, proteins, and growth factors — and purify it into a sterile, injectable solution.
This formulation contains no living cells but maintains the regenerative “language” of stem cells, capable of activating repair mechanisms in the recipient tissue.
In essence, Alloblast communicates with your own scalp cells — signaling them to heal, renew, and regenerate.
A New Era in Regenerative Medicine
Traditional regenerative methods such as PRP (Platelet-Rich Plasma) or autologous stem cell injections depend on the patient’s biological condition, making outcomes inconsistent.
Alloblast overcomes this limitation by providing standardized, potent, and safe regenerative factors that work reliably in all patients — independent of age or health status.
This makes it a cutting-edge alternative for individuals seeking biological rejuvenation without cell extraction or surgery.
How Alloblast Therapy Works
The treatment works by reawakening the scalp’s natural regenerative network through precise biochemical communication.
The injected fibroblast-derived factors bind to receptors on the surface of scalp and follicle cells, activating a cascade of biological responses that encourage growth and repair.
Key Mechanisms of Action
- Stimulation of Growth Pathways
Bioactive proteins such as FGF (Fibroblast Growth Factor) and EGF (Epidermal Growth Factor) stimulate cellular activity, leading to enhanced collagen synthesis, angiogenesis (formation of new blood vessels), and follicle regeneration. - Activation of Native Stem Cells
Although Alloblast itself is cell-free, it triggers resident stem cells in the scalp to multiply and differentiate, restoring the vitality of aging or damaged follicles. - Regulation of Inflammation
Chronic micro-inflammation is a major contributor to hair loss. Alloblast contains anti-inflammatory cytokines that help restore immune balance, improving scalp health. - Microcirculation Improvement
The therapy promotes the production of vascular growth factors, enhancing oxygen and nutrient delivery to the follicle roots. - Matrix Remodeling
Fibroblast factors increase collagen and elastin in the scalp’s extracellular matrix, strengthening follicular support structures and improving elasticity.
The Procedure
- The therapy is performed under sterile conditions in a dermatological setting.
- The Alloblast solution is applied via microinjections across the affected scalp areas.
- A session takes 30–45 minutes, and patients can resume daily activities immediately.
No tissue harvesting, centrifugation, or recovery period is required — making Alloblast one of the simplest yet most biologically advanced treatments available today.
Benefits for Hair and Scalp Health
The effects of Alloblast Therapy extend beyond surface improvement. It works on a cellular level, promoting long-term regeneration rather than temporary stimulation.
Clinical Benefits
- Revives Dormant Hair Follicles – Reactivates inactive follicles and extends the hair’s growth phase.
- Improves Hair Density and Thickness – Increases follicular diameter, leading to visibly stronger strands.
- Reduces Hair Shedding – Normalizes the hair cycle, minimizing excessive loss.
- Accelerates Tissue Repair – Speeds up recovery after transplantation or scalp irritation.
- Balances Scalp Microenvironment – Reduces dryness, flaking, and inflammation.
- Enhances Blood Flow and Oxygenation – Supports a healthier scalp vascular network.
- Delays Biological Aging – Promotes collagen renewal and reduces oxidative stress, preserving long-term follicle vitality.
The result is a scalp that feels healthier, denser, and more resilient — forming the ideal foundation for lasting hair restoration.
Doku Clinic is a brand of Dr. Serkan Aygın.
Alloblast vs. Traditional PRP or Stem Cell Treatments
Although PRP and stem cell therapies remain valuable tools in regenerative dermatology, Alloblast represents a third-generation advancement in this field.
| Feature | Alloblast (Fibroblast) Therapy | PRP (Platelet-Rich Plasma) | Autologous Stem Cell Therapy |
| Source | Donor fibroblast-derived proteins | Patient’s blood platelets | Patient’s fat or tissue |
| Cell Content | Cell-free (acellular) | Platelets only | Live stem cells |
| Regenerative Potential | Very high | Moderate | High |
| Consistency of Results | Stable and standardized | Variable (patient-dependent) | Variable (extraction-dependent) |
| Procedure Type | Injection, no harvesting | Blood draw + injection | Surgical extraction |
| Downtime | None | Minimal | Moderate |
| Pain Level | Very low | Mild | Moderate |
| Safety Profile | Immunologically safe | Safe but patient-dependent | Safe but invasive |
Clinical Perspective
Alloblast bridges the gap between convenience and potency — providing high-level regenerative signaling with the ease and comfort of PRP.
It is particularly beneficial for patients who:
- Cannot undergo autologous stem cell harvesting
- Seek standardized, reproducible outcomes
- Want rapid recovery and minimal invasiveness
Pre- and Post-Hair Transplant Applications
At Dr. Serkan Aygın Clinic, Alloblast is strategically integrated into both pre-transplant and post-transplant phases to optimize every stage of the patient journey.
Before Hair Transplantation
Alloblast Therapy prepares the scalp for surgery by improving its biological condition.
Benefits of Pre-Transplant Application:
- Increases skin elasticity, making implantation easier and safer
- Improves vascularity of both donor and recipient areas
- Reduces baseline inflammation and oxidative stress
- Strengthens existing follicles, improving overall scalp health
- Optimizes the healing response for smoother recovery post-surgery
By ensuring that the scalp and follicles are biologically active and healthy, Alloblast sets the stage for higher graft survival rates and improved final density.
After Hair Transplantation
Post-operative tissue recovery is a crucial determinant of long-term success.
Benefits of Post-Transplant Application:
Accelerates wound healing and tissue regeneration.
Supports new vessel formation around grafts for faster integration.
Reduces post-surgical redness, swelling, and discomfort.
Prevents shock loss by stabilizing the surrounding native hair.
Enhances the overall density and texture of transplanted hair.
By combining medical expertise with regenerative technology, the clinic’s team ensures that each transplant achieves maximum survival and natural growth potential.
Who Can Benefit from Alloblast Therapy?
Because it is cell-free and biocompatible, Alloblast can be safely used in nearly all patients, regardless of age or skin type.
Treatment Protocol and Expectations
A complete Alloblast program is personalized according to the patient’s needs and scalp condition.
- Number of Sessions: 3–4, spaced 2–4 weeks apart.
- Session Duration: Approximately 30–45 minutes.
- Results Timeline: Early improvements in 4–6 weeks; visible thickening by 3–6 months.
- Maintenance: Every 6–12 months to sustain optimal scalp health.
Patients experience minimal discomfort and no downtime. Following each session, only mild redness may occur, subsiding within hours.
Why Choose Dr. Serkan Aygın Clinic for Regenerative Hair Care
Collaborative Excellence in Regenerative Hair Care
Every Alloblast protocol at Dr. Serkan Aygın Clinic is supported by a multidisciplinary collaboration with Doku Clinic, a leading center for medical aesthetics and plastic surgery.
Founded in 2017 by Dr. Serkan Aygın and Melda Aygın, Doku Clinic and Dr. Serkan Aygın Clinic operate within the same medical ecosystem — uniting expertise in hair transplantation. This integrated structure combines clinical excellence, innovation, and aesthetic vision, ensuring that every treatment reflects world-class standards of safety, quality, and patient care.
This partnership blends medical artistry, dermatological expertise, and advanced technology, ensuring that every stage of treatment meets the highest international standards of safety, precision, and patient care.
Key Advantages
Dermatological Expertise: Each treatment is supervised by certified dermatologists and regenerative medicine specialists working within our joint clinical ecosystem.
Integrated Approach: Regenerative solutions such as Alloblast, Exosome, Magellan PRP, and Autologous Stem Cell Therapy are harmonized to support both scalp and skin health.
World-Class Standards: All applications are performed in sterile, internationally accredited environments that meet global safety and quality criteria.
Personalized Medical Care: Every protocol is tailored to the patient’s unique biological profile, ensuring precise, natural, and lasting outcomes.
Continuous Follow-Up: Post-treatment care and monitoring are jointly managed to optimize long-term scalp vitality and patient satisfaction.
Together, Dr. Serkan Aygın Clinic and Doku Clinic redefine the standard of regenerative hair and scalp therapy — merging science, dermatology, and artistry to deliver exceptional, globally recognized results.
Understanding the Role of Alloblast Therapy in Hair Restoration
Alloblast (Fibroblast) Stem Cell Therapy reflects a progressive shift in hair restoration, offering patients a non-invasive, biologically advanced way to support and rejuvenate hair growth.
By stimulating the scalp’s natural regenerative pathways, this therapy improves both the strength and quality of hair over time.
At Dr. Serkan Aygın Clinic, we use Alloblast therapy within an integrated, scientifically backed framework — designed to provide long-term benefits for those seeking hair restoration, whether before or after hair transplant surgery.
Through cutting-edge science and a personalized approach, we help patients restore not only their hair but their confidence, providing a holistic solution for long-lasting results.
Frequently Asked Questions
Is the treatment safe?
Yes. It is a certified, cell-free formulation derived from screened fibroblast cultures processed under Good Manufacturing Practice (GMP) standards. There is no risk of immune reaction or rejection.
How many sessions will I need?
Most patients benefit from 3–4 sessions spaced a few weeks apart. Maintenance once or twice a year helps sustain long-term scalp vitality.
When will I see the results?
When will I see the results?
You may notice scalp vitality improvements after the first month, with measurable thickening and density over 3–6 months.
Can Alloblast replace hair transplantation?
It cannot replace transplantation in advanced baldness but serves as a powerful complementary treatment, improving results and extending the life of both native and transplanted hair.
Can it be combined with other therapies?
Yes. It pairs effectively with PRP, Exosome therapy, and Mesotherapy, depending on your treatment plan.
